Potential Use of Silver Nanoparticles on Pathogenic Bacteria, their Toxicity and Possible Mechanisms of Action

نویسندگان

  • Nelson Durán
  • Priscyla D. Marcato
  • Roseli De Conti
  • Oswaldo L. Alves
  • Fabio T. M. Costa
  • Marcelo Brocchi
چکیده

As propriedades da prata são conhecidas há muitos anos. Recentemente, as nanopartículas de prata têm chamado a atenção por sua atividade antimicrobiana que oferece a possibilidade de uso com propósitos médicos e de higiene. Estas nanopartículas de prata em diferentes formulações, com diferentes formas e tamanhos, exibem atividades antimicrobianas diferentes. Entretanto, os mecanismos da atividade antimicrobiana de íons e de nanopartículas, assim como sua toxicidade em tecidos humanos não estão totalmente esclarecidos. Esta revisão avalia o uso potencial de nanopartículas de prata no controle de patogênicos com ênfase sobre sua ação contra bactérias patogênicas, sua toxicidade e possíveis mecanismos de ação.

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تاریخ انتشار 2010